Woman’s rare genetic disorder could hold the key to weight loss

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AUSTIN, Texas– Abby Solomon’s handbag appears like a taking a trip kitchen, loaded with sweet snacks.

“My life generally revolves around food,” she said.And yet for all

she consumes, she remains in a continuous fight with starvation.


CBS News Abby was born with an uncommon hereditary disorder called neonatal progeroid syndrome. The anomaly mangles noses and makes Abby look too soon old.

It likewise avoids her body from making adequate asprosin, a hormone that promotes cravings.

She’s not hungry however still needs to consume all the time. The food feeds her brain simply enough glucose to keep her from passing out.

However after a couple of bites, she feels complete. Abby takes in half the amount of typical calories for a woman her age; and at 5 feet 10 inches, weighs simply 99 pounds.She’s eating, however not putting on weight.”I indicate, it’s weird.

I agree,”Abby said.Dr. Atul Chopra doesn’t believe it’s strange.”I think we are extremely

fortunate that our courses crossed, mine and Abby’s, “Chopra said.He thinks it could be an exciting advancement in the fight against obesity and diabetes. CBS News A geneticist at Baylor College of Medicine in Houston, Chopra analyzed Abby’s DNA and replicated her condition in laboratory mice.He’s now

developing an antibody developed to shut down aprosin’s result on the body.”That would be the hope here, that … we can inject diabetic overweight human beings with an antibody against asprosin. And if it works anything like how it operates in

mice, then I believe we have a video game changer, “Chopra said.It certainly would be for Thomeshia Jones.”I do not like looking at myself in the mirror, “she said.At 17 years of ages, she weighs 380 pounds.” I was getting badgered every day. Like, non-stop, every day,”she said.

CBS News While Thomeshia is learning much better eating routines at Texas Kid’s Health center teenage weight problems program, she is desperate.Next month, she will have bariatric surgery, which is something she would”certainly”avoid if she could.”Just the idea of surgery is scary.

if there’s a way I can go about it without surgical treatment, I’m ready to do that,”she said.Which is simply exactly what Abby Solomon’s DNA might soon

provide in the fight against obesity and diabetes.”That’s so cool, “Abby stated.” I guess that’s exactly what I was put here to do. And that’s why I was born this method. “Lastly, Abby’s hunger is ravenous; Hungry to help.

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